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Serum creatine kinase and creatinine in adult spinal muscular atrophy under nusinersen treatment

Abstract Objective To determine whether serum creatine kinase activity (CK) and serum creatinine concentration (Crn) are prognostic and predictive biomarkers for disease severity, disease progression, and nusinersen treatment effects in adult patients with 5q‐associated spinal muscular atrophy (SMA)...

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Principais autores: Maren Freigang, Claudia D. Wurster, Tim Hagenacker, Benjamin Stolte, Markus Weiler, Christoph Kamm, Olivia Schreiber‐Katz, Alma Osmanovic, Susanne Petri, Alexander Kowski, Thomas Meyer, Jan C. Koch, Isabell Cordts, Marcus Deschauer, Paul Lingor, Elisa Aust, Daniel Petzold, Albert C. Ludolph, Björn Falkenburger, Andreas Hermann, René Günther
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley 2021-05-01
coleção:Annals of Clinical and Translational Neurology
Acesso em linha:https://doi.org/10.1002/acn3.51340
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