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Cells responsible for liver mass regeneration in rats with 2-acetylaminofluorene/partial hepatectomy injury

Abstract Background Whether hepatic progenitor cells (HPCs)/oval cells regenerate liver mass upon chronic liver injury is controversial in mice and has not been conclusively proven in humans and rats. In this study, we examined which cell type—hepatocytes or oval cells—mediates liver regeneration in...

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Principais autores: Chin-Sung Chien, Ya-Hui Chen, Hui-Ling Chen, Chiu-Ping Wang, Shang-Hsin Wu, Shu-Li Ho, Wen-Cheng Huang, Chun-Hsien Yu, Mei-Hwei Chang
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2018-04-01
Series:Journal of Biomedical Science
Assuntos:
AAF/PH
Ductular reaction
Hepatocyte
Liver injury
Oval cells
Rat
Acceso en liña:http://link.springer.com/article/10.1186/s12929-018-0441-5
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