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Development of a novel in vitro assay to screen for neuroprotective drugs against iatrogenic neurite shortening.

This work tries to help overcome the lack of relevant translational screening assays, as a limitation for the identification of novel analgesics for neuropathic pain. Hyperexcitability and neurite shortening are common adverse effects of antiviral and antitumor drugs, leading to neuropathic pain. No...

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Principais autores: Antón L Martínez, José Brea, Mateo Barro, Xavier Monroy, Manuel Merlos, Javier Burgueño, María Isabel Loza
格式: Artigo
語言:Inglês
出版: Public Library of Science (PLoS) 2021-01-01
叢編:PLoS ONE
在線閱讀:https://doi.org/10.1371/journal.pone.0248139
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