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The single-cell atlas of colorectal cancer reveals cellular heterogeneity and key molecular features of the tumor immune microenvironment

Abstract Background Colorectal cancer (CRC) is a highly heterogeneous malignancy, with its tumor immune microenvironment (TIME) playing a crucial role in tumor progression, immune evasion, and treatment response. Despite insights from single-cell technologies, challenges such as small samples and in...

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Principais autores: JunHu Li, ZhiQiang Liu, BoYu Zhang, LiuPing You, YueNan Huang
Formato: Artigo
Idioma:Inglês
Publicado: Springer 2025-10-01
Series:Cancer Immunology, Immunotherapy
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Acceso en liña:https://doi.org/10.1007/s00262-025-04173-2
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