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Porphyrins produced by acneic Cutibacterium acnes strains activate the inflammasome by inducing K+ leakage

Summary: Some Cutibacterium acnes subgroups dominate on healthy skin, whereas others are frequently acne associated. Here we provide mechanistic insights into this difference, using an anaerobic keratinocyte-sebocyte-C. acnes co-culture model. An acneic C. acnes strain as well as its porphyrins acti...

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I tiakina i:
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Ngā kaituhi matua: Karl-Jan Spittaels, Katleen van Uytfanghe, Christos C. Zouboulis, Christophe Stove, Aurélie Crabbé, Tom Coenye
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Elsevier 2021-06-01
Rangatū:iScience
Ngā marau:
Urunga tuihono:http://www.sciencedirect.com/science/article/pii/S2589004221005435
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