Uncoupling antisense-mediated silencing and DNA methylation in the imprinted Gnas cluster.

There is increasing evidence that non-coding macroRNAs are major elements for silencing imprinted genes, but their mechanism of action is poorly understood. Within the imprinted Gnas cluster on mouse chromosome 2, Nespas is a paternally expressed macroRNA that arises from an imprinting control regio...

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Detalhes bibliográficos

Principais autores:	Christine M Williamson, Simon T Ball, Claire Dawson, Stuti Mehta, Colin V Beechey, Martin Fray, Lydia Teboul, T Neil Dear, Gavin Kelsey, Jo Peters
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Public Library of Science (PLoS) 2011-03-01
Colecção:	PLoS Genetics
Acesso em linha:	https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1001347&type=printable
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