Phase 1 study of quercetin, a natural antioxidant for children and young adults with Fanconi anemia

Abstract: Fanconi anemia (FA) is a rare inherited disorder characterized by progressive bone marrow failure (BMF) and a predisposition to malignancy. Systemic reactive oxygen species (ROS) and increased sensitivity of FA hematopoietic progenitors to ROS play a key role in the pathogenesis of BMF. Tr...

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Autori principali:	Parinda A. Mehta, Adam Nelson, Sara Loveless, Adam Lane, Tsuyoshi Fukuda, Ashley Teusink-Cross, Deborah Elder, Denise Lagory, Erica Miller, Jose A. Cancelas, Jonathan Howell, Junfang Zhao, Kana Mizuno, Kasiani C. Myers, Kelly Lake, Kelly McIntosh, Kenneth D. R. Setchell, Nathan Luebbering, Stephanie Edwards, Tafadzwa Chihanga, Susanne I. Wells, Stella M. Davies
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2025-04-01
Serie:	Blood Advances
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2473952925000308
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