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Insight into pathogenomics and phylogeography of hypervirulent and highly-lethal Mycobacterium tuberculosis strain cluster

Abstract Background . The Mycobacterium tuberculosis Beijing genotype is globally spread lineage with important medical properties that however vary among its subtypes. M. tuberculosis Beijing 14717-15-cluster was recently discovered as both multidrug-resistant, hypervirulent, and highly-lethal stra...

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Principais autores: Igor Mokrousov, Anna Vyazovaya, Egor Shitikov, Maria Badleeva, Olesya Belopolskaya, Dmitry Bespiatykh, Alena Gerasimova, Panayotis Ioannidis, Weiwei Jiao, Polina Khromova, Aleksey Masharsky, Dinara Naizabayeva, Dimitrios Papaventsis, Oksana Pasechnik, João Perdigão, Nalin Rastogi, Adong Shen, Viacheslav Sinkov, Yuriy Skiba, Natalia Solovieva, Silva Tafaj, Violeta Valcheva, Irina Kostyukova, Svetlana Zhdanova, Viacheslav Zhuravlev, Oleg Ogarkov
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2023-06-01
Serier:BMC Infectious Diseases
Fag:
Mycobacterium tuberculosis
Whole genome sequencing
Virulence
Drug resistance
Beijing genotype
Online adgang:https://doi.org/10.1186/s12879-023-08413-7
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