LINC complex protein nesprin-2 has pro-apoptotic activity via Bcl-2 family proteins
Abstract The apoptotic intrinsic pathway is initiated by perforation of the mitochondrial outer membrane by the effector pro-apoptotic proteins of the Bcl-2 family, Bax and Bak. Bax and Bak need to be activated, a process facilitated by the action of BH3-only pro-apoptotic members of the Bcl-2 famil...
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| Principais autores: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2024-01-01
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| Colecção: | Cell Death Discovery |
| Acesso em linha: | https://doi.org/10.1038/s41420-023-01763-w |
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