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Hypomethylation of VTRNA2-1 promoter predicts adverse outcomes in peripheral artery disease

Abstract Background Peripheral artery disease (PAD) is a progressive vascular condition with high risks of limb amputation and adverse clinical outcomes. Despite advancements in revascularization techniques, risk stratification remains limited, especially in predicting long-term limb-specific compli...

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Principais autores: Ming-Lung Tsai, Yi-Chun Huang, Ming-Yun Ho, Jih-Kai Yeh, Chun-Chi Chen, Chin-Yuan Chia, Wen-Lang Fan, I-Chang Hsieh, Chi-Neu Tsai, Chao-Yung Wang
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2026-02-01
Serier:Clinical Epigenetics
Fag:
Peripheral artery disease
Epigenetics
DNA methylation
VTRNA2-1
Biomarker
Cardiovascular outcomes
Online adgang:https://doi.org/10.1186/s13148-026-02087-z
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