A systematic investigation of the effects of TGF-β3 and mechanical stimulation on tenogenic differentiation of mesenchymal stromal cells in a poly(ethylene glycol)/gelatin-based hydrogel

Background: High post-surgical failure rates following tendon injury generate high medical costs and poor patient recovery. Cell-based tendon tissue engineering has the potential to produce fully functional replacement tissue and provide new strategies to restore tendon function and healing. In this...

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Hlavní autoři:	Ilze Donderwinkel, Rocky S. Tuan, Neil R. Cameron, Jessica E. Frith
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2023-11-01
Edice:	Journal of Orthopaedic Translation
Témata:	Biochemical stimulation Hydrogels Mesenchymal stromal cells Physical stimulation Tendon tissue engineering Tenogenic differentiation
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2214031X23000670
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