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The ischaemic preconditioning paradox and its implications for islet isolation from heart-beating and non heart-beating donors

Abstract The impact of ischaemia can severely damage procured donor organs for transplantation. The pancreas, and pancreatic islets in particular, is one of the most sensitive tissues towards hypoxia. The present study was aimed to assess the effect of hypoxic preconditioning (HP) performed ex-vivo...

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書誌詳細
主要な著者: Daniel Brandhorst, Heide Brandhorst, Samuel Acreman, Paul R. V. Johnson
フォーマット: Artigo
言語:Inglês
出版事項: Nature Portfolio 2022-11-01
シリーズ:Scientific Reports
オンライン・アクセス:https://doi.org/10.1038/s41598-022-23862-x
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