Glutathione peroxidase 4 and vitamin E control reticulocyte maturation, stress erythropoiesis and iron homeostasis

Glutathione peroxidase 4 (GPX4) is unique as it is the only enzyme that can prevent detrimental lipid peroxidation in vivo by reducing lipid peroxides to the respective alcohols thereby stabilizing oxidation products of unsaturated fatty acids. During reticulocyte maturation, lipid peroxidation medi...

Full description

Bibliographic Details

Main Authors:	Sandro Altamura, Naidu M. Vegi, Philipp S. Hoppe, Timm Schroeder, Michaela Aichler, Axel Walch, Katarzyna Okreglicka, Lothar Hültner, Manuela Schneider, Camilla Ladinig, Cornelia Kuklik-Roos, Josef Mysliwietz, Dirk Janik, Frauke Neff, Birgit Rathkolb, Mar tin Hrabé de Angelis, Christian Buske, Ana Rita da Silva, Katja Muedder, Marcus Conrad, Tomas Ganz, Manfred Kopf, Martina U. Muckenthaler, Georg W. Bornkamm
Format:	Artigo
Language:	Inglês
Published:	Ferrata Storti Foundation 2020-04-01
Series:	Haematologica
Online Access:	https://haematologica.org/article/view/9330
Tags:	Add Tag No Tags, Be the first to tag this record!