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Attomole-per Cell Atomic Mass Spectrometry Measurement of Platinum and Gold Drugs in Cultured Lung Cancer Cells

In this study, we developed a strategy to determine atto- and femtomolar amounts of metal ions in lysates and mineralizates of cells (human non-small-cell lung carcinoma (NSCLC, A549) and normal lung (MRC-5)) exposed to cytotoxic metallo-drugs: cisplatin and auranofin at concentrations close to the...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Wioletta Jakubczak, Maja Haczyk-Więcek, Katarzyna Pawlak
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2021-12-01
Schriftenreihe:Molecules
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Online-Zugang:https://www.mdpi.com/1420-3049/26/24/7627
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