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Two separate interfaces between the voltage sensor and pore are required for the function of voltage-dependent K(+) channels.

Voltage-dependent K(+) (Kv) channels gate open in response to the membrane voltage. To further our understanding of how cell membrane voltage regulates the opening of a Kv channel, we have studied the protein interfaces that attach the voltage-sensor domains to the pore. In the crystal structure, th...

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Principais autores: Seok-Yong Lee, Anirban Banerjee, Roderick MacKinnon
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science (PLoS) 2009-03-01
Series:PLoS Biology
Acceso en liña:http://europepmc.org/articles/PMC2650729?pdf=render
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