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PD-1 inhibitor inducing exosomal miR-34a-5p expression mediates the cross talk between cardiomyocyte and macrophage in immune checkpoint inhibitor–related cardiac dysfunction

Background Immune checkpoint inhibitors (ICIs) have been an important therapeutic advancement in the field of cancer medicine. Recent reports provided greater insights into the cardiovascular adverse events, which prohibited the use of ICIs. Cardiovascular adverse events occur in different forms, su...

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Auteurs principaux: Wenzheng Xia, Hanbin Chen, Didi Chen, Yijia Ye, Congying Xie, Meng Hou
Format: Artigo
Langue:Inglês
Publié: BMJ Publishing Group 2020-10-01
Collection:Journal for ImmunoTherapy of Cancer
Accès en ligne:https://jitc.bmj.com/content/8/2/e001293.full
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