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Exhausted natural killer cells in adult IgA vasculitis

Abstract Introduction IgA vasculitis nephritis (IgAVN) manifests in up to 84% of adult patients with IgA vasculitis (IgAV) and is associated with an elevated risk of progression to chronic kidney failure. The underlying pathogenic mechanism of adult IgAVN in leukocytes remain largely uncharacterised...

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Autori principali: Matija Bajželj, Emanuela Senjor, Nika Boštic, Matjaž Hladnik, Snežna Sodin-Šemrl, Milica Perišić Nanut, Janko Kos, Alojz Ihan, Alojzija Hočevar, Andreja Nataša Kopitar, Katja Lakota
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2025-04-01
Serie:Arthritis Research & Therapy
Soggetti:
IgA vasculitis
Adults
RNA sequencing
Nephritis
Natural killer cells
Accesso online:https://doi.org/10.1186/s13075-025-03559-y
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