Two activating mutations of MPL in triple‐negative myeloproliferative neoplasms

Abstract MPLW515K or W515L mutation plays an important role in the pathogenesis of myeloproliferative neoplasms (MPNs) through signaling molecules of the cytokine receptor axis. Besides MPLW515K or W515L, more than 30 atypical MPL mutations have been reported in patients who are negative for JAK2V61...

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Bibliografski detalji

Glavni autori:	Juan Xie, Xiuhua Chen, Feng Gao, Ruixia Hou, Tingting Tian, Yaofang Zhang, Lifang Fan, Jinjun Hu, Guiyang Zhu, Wanfang Yang, Hongwei Wang
Format:	Artigo
Jezik:	Inglês
Izdano:	Wiley 2019-09-01
Serija:	Cancer Medicine
Teme:	molecular pathology MPL mutation triple-negative myeloproliferative neoplasms
Online pristup:	https://doi.org/10.1002/cam4.2387
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