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Respiratory syncytial virus interferon antagonist NS1 protein suppresses and skews the human T lymphocyte response.

We recently demonstrated that the respiratory syncytial virus (RSV) NS1 protein, an antagonist of host type I interferon (IFN-I) production and signaling, has a suppressive effect on the maturation of human dendritic cells (DC) that was only partly dependent on released IFN-I. Here we investigated w...

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Detalhes bibliográficos
Principais autores: Shirin Munir, Philippa Hillyer, Cyril Le Nouën, Ursula J Buchholz, Ronald L Rabin, Peter L Collins, Alexander Bukreyev
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2011-04-01
coleção:PLoS Pathogens
Acesso em linha:http://europepmc.org/articles/PMC3080852?pdf=render
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