Quantifying Isoprenoids in the Ergosterol Biosynthesis by Gas Chromatography–Mass Spectrometry

The ergosterol pathway is a promising target for the development of new antifungals since its enzymes are essential for fungal cell growth. Appropriate screening assays are therefore needed that allow the identification of potential inhibitors. We developed a whole-cell screening method, which can b...

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Hlavní autoři:	Maximilian Liebl, Ludwig Huber, Hesham Elsaman, Petra Merschak, Johannes Wagener, Fabio Gsaller, Christoph Müller
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2023-07-01
Edice:	Journal of Fungi
Témata:	<i>Aspergillus fumigatus</i> <i>erg1</i> <i>erg9</i> ergosterol biosynthesis farnesol GC-MS
On-line přístup:	https://www.mdpi.com/2309-608X/9/7/768
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