Integrated salivary microbiome and metabolome profiling reveals ecological and functional alterations in severe early childhood caries

Abstract Background Early childhood caries (ECC), particularly severe early childhood caries (S-ECC), remains a prevalent chronic disease, significantly affecting children’s health and quality of life. Despite extensive research, the detailed ecological and metabolic shifts underlying S-ECC pathogen...

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Huvudupphov:	Yaqi Liu, Shuxing Yu, Xinyue Wang, Dingwei Ye, Munire Aili, Xiangqing Fu, Jing Zou, Qizhao Ma
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	BMC 2025-12-01
Serie:	Journal of Translational Medicine
Ämnen:	Severe early childhood caries Salivary microbiome Salivary metabolome Amino acid metabolism Biomarker
Länkar:	https://doi.org/10.1186/s12967-025-07541-9
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