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Mild hyperthermia enhanced synergistic uric acid degradation and multiple ROS elimination for an effective acute gout therapy

Abstract Background Acute gouty is caused by the excessive accumulation of Monosodium Urate (MSU) crystals within various parts of the body, which leads to a deterioration of the local microenvironment. This degradation is marked by elevated levels of uric acid (UA), increased reactive oxygen specie...

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Bibliografiske detaljer
Principais autores: Pei Zhao, Hua-Zhong Hu, Xiao-Tong Chen, Qi-Yun Jiang, Xue-Zhao Yu, Xiao-Lin Cen, Shi-Qing Lin, Sui-qing Mai, Wei-lin Pang, Jin-Xiang Chen, Qun Zhang
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2024-05-01
Serier:Journal of Nanobiotechnology
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Online adgang:https://doi.org/10.1186/s12951-024-02539-9
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