MHCII-peptide presentation: an assessment of the state-of-the-art prediction methods

Major histocompatibility complex Class II (MHCII) proteins initiate and regulate immune responses by presentation of antigenic peptides to CD4+ T-cells and self-restriction. The interactions between MHCII and peptides determine the specificity of the immune response and are crucial in immunotherapy...

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Bibliographic Details

Main Authors:	Yaqing Yang, Zhonghui Wei, Gabriel Cia, Xixi Song, Fabrizio Pucci, Marianne Rooman, Fuzhong Xue, Qingzhen Hou
Format:	Artigo
Language:	Inglês
Published:	Frontiers Media S.A. 2024-03-01
Series:	Frontiers in Immunology
Subjects:	MHCII peptide binding prediction immunology bioinformatics webserver machine learning
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1293706/full
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