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A Mitochondrial ATP Synthase Subunit Interacts with TOR Signaling to Modulate Protein Homeostasis and Lifespan in Drosophila

Diet composition is a critical determinant of lifespan, and nutrient imbalance is detrimental to health. However, how nutrients interact with genetic factors to modulate lifespan remains elusive. We investigated how diet composition influences mitochondrial ATP synthase subunit d (ATPsyn-d) in modul...

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Autori principali: Xiaoping Sun, Charles T. Wheeler, Jason Yolitz, Mara Laslo, Thomas Alberico, Yaning Sun, Qisheng Song, Sige Zou
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2014-09-01
Serie:Cell Reports
Accesso online:http://www.sciencedirect.com/science/article/pii/S2211124714006858
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