Cocrystal-inspired glycyrrhizic acid–azole nanoassemblies for synergistic biofilm disruption and immune modulation in fungal infections

Abstract Fungal biofilms represent a major therapeutic hurdle due to their drug resistance and immune evasion. Here, we report a cocrystal-inspired nano-assembly strategy that co-assembles glycyrrhizic acid (GA), a natural triterpenoid saponin, with azole antifungal agents into multifunctional nanop...

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Bibliografski detalji

Glavni autori:	Chen Wang, Chang Gao, Linna Qian, Min Chen, Yuanfeng Li, Sunsong Ye, Wenpin Cai, Tiansheng Xu, Lifei Zheng, Yong Liu, Yijie Chen, Linqi Shi, Lei Zhao
Format:	Artigo
Jezik:	Inglês
Izdano:	BMC 2026-01-01
Serija:	Journal of Nanobiotechnology
Teme:	Combination therapy Biofilm Self-assembly Herbal medicines Synergistic effect
Online pristup:	https://doi.org/10.1186/s12951-025-04014-5
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