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A novel mRNA decay inhibitor abolishes pathophysiological cellular transition

Abstract In cells, mRNA synthesis and decay are influenced by each other, and their balance is altered by either external or internal cues, resulting in changes in cell dynamics. We previously reported that it is important that an array of mRNAs that shape a phenotype are degraded before cellular tr...

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Autors principals: Daisuke Kami, Toshimasa Ishizaki, Toshihiko Taya, Akira Katoh, Hiroyuki Kouji, Satoshi Gojo
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2022-06-01
Col·lecció:Cell Death Discovery
Accés en línia:https://doi.org/10.1038/s41420-022-01076-4
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