RSK1 vs. RSK2 Inhibitory Activity of the Marine β-Carboline Alkaloid Manzamine A: A Biochemical, Cervical Cancer Protein Expression, and Computational Study

Manzamines are complex polycyclic marine-derived β-carboline alkaloids with reported anticancer, immunostimulatory, anti-inflammatory, antibacterial, antiviral, antimalarial, neuritogenic, hyperlipidemia, and atherosclerosis suppression bioactivities, putatively associated with inhibition of glycoge...

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Detalhes bibliográficos

Principais autores:	Alejandro M. S. Mayer, Mary L. Hall, Joseph Lach, Jonathan Clifford, Kevin Chandrasena, Caitlin Canton, Maria Kontoyianni, Yeun-Mun Choo, Dev Karan, Mark T. Hamann
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2021-09-01
coleção:	Marine Drugs
Assuntos:	MZA Manzamine A CTKD C-terminal kinase domain ras-ERK1/2 (extracellular-signal-regulated kinase 1/2) pathway RSK1
Acesso em linha:	https://www.mdpi.com/1660-3397/19/9/506
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