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Characterization the response of Korl:ICR mice to loperamide induced constipation

Abstract Animal models of constipation induced with drugs and diet have been widely employed to investigate therapeutic effects and the action mechanism of drugs against this disease. ICR mice were selected to produce this disease model through oral administration of loperamide (Lop), even though SD...

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Principais autores: Ji Eun Kim, Woo Bin Yun, Ji Eun Sung, Hyun Ah Lee, Jun Young Choi, Yeon Shik Choi, Young Suk Jung, Kil Soo Kim, Dae Youn Hwang
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2016-12-01
Serier:Laboratory Animal Research
Fag:
Korl:ICR
constipation
loperamide
excretion parameters
mucin secretion
Online adgang:http://link.springer.com/article/10.5625/lar.2016.32.4.231
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