X-ray crystal structure of plasmin with tranexamic acid–derived active site inhibitors
Abstract: The zymogen protease plasminogen and its active form plasmin perform key roles in blood clot dissolution, tissue remodeling, cell migration, and bacterial pathogenesis. Dysregulation of the plasminogen/plasmin system results in life-threatening hemorrhagic disorders or thrombotic vascular...
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| Principais autores: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2017-05-01
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| coleção: | Blood Advances |
| Acesso em linha: | http://www.sciencedirect.com/science/article/pii/S2473952920301853 |
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