Tau-PET pathology in the subregions of the amygdala and its associations with cognitive performance and neuropsychiatric symptoms in autosomal dominant Alzheimer’s disease

Abstract Background The amygdala plays a role in behavior and emotional response and is vulnerable to Alzheimer’s disease (AD) pathology, yet little is known about amygdala tau accumulation before clinical symptom onset. To investigate whether certain amygdala nuclei are particularly vulnerable to d...

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Principais autores:	Catarina Tristão-Pereira, Stephanie Langella, Justin S. Sanchez, Vincent Malotaux, Bing He, Jorge Alcina, Jairo E. Martinez, Zoe Rubinstein, Ana Baena, Clara Vila-Castelar, Averi Giudicessi, Liliana Ramirez Gomez, Claudia Ramos, Daniel Vasquez, David Aguillon, Heidi I. L. Jacobs, Reisa A. Sperling, Keith Johnson, Jennifer R. Gatchel, Yakeel T. Quiroz
Format:	Artigo
Jezik:	Inglês
Izdano:	BMC 2025-03-01
Serija:	Alzheimer’s Research & Therapy
Teme:	Autosomal-dominant Alzheimer’s disease Neuropsychiatric symptoms Tau pathology Amygdala PET imaging
Online dostop:	https://doi.org/10.1186/s13195-025-01711-z
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