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Binding of the Treslin-MTBP Complex to Specific Regions of the Human Genome Promotes the Initiation of DNA Replication

Summary: The processes that control where higher eukaryotic cells initiate DNA replication throughout the genome are not understood clearly. In metazoans, the Treslin-MTBP complex mediates critical final steps in formation of the activated replicative helicase prior to initiation of replication. Her...

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Autors principals: Akiko Kumagai, William G. Dunphy
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2020-09-01
Col·lecció:Cell Reports
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Accés en línia:http://www.sciencedirect.com/science/article/pii/S2211124720311670
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