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Human Properdin Released By Infiltrating Neutrophils Can Modulate Influenza A Virus Infection

The complement system is designed to recognise and eliminate invading pathogens via activation of classical, alternative and lectin pathways. Human properdin stabilises the alternative pathway C3 convertase, resulting in an amplification loop that leads to the formation of C5 convertase, thereby act...

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Principais autores: Praveen M. Varghese, Shuvechha Mukherjee, Futwan A. Al-Mohanna, Souad M. Saleh, Fahad N. Almajhdi, Nazar Beirag, Saad H. Alkahtani, Reena Rajkumari, Beatrice Nal Rogier, Robert B. Sim, Susan Idicula-Thomas, Taruna Madan, Valarmathy Murugaiah, Uday Kishore
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021-12-01
Serier:Frontiers in Immunology
Fag:
innate immune system
complement system
complement evasion
human properdin
RNA viruses
influenza A virus
Online adgang:https://www.frontiersin.org/articles/10.3389/fimmu.2021.747654/full
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