Immunosuppression of Tumor-Derived Factors Modulated Neutrophils in Upper Tract Urothelial Carcinoma Through Upregulation of Arginase-1 via ApoA1-STAT3 Axis

Upper tract urothelial carcinoma (UTUC) presents aggressive features and a tumor microenvironment with T cell depletion. However, the role of tumor-associated neutrophils in UTUC remains unclear. This study aimed to investigate how UTUC tumor-derived factors modulate neutrophils and their impact on...

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Hlavní autoři:	Chih-Chia Chang, Chia-Bin Chang, Cheng-Huang Shen, Ming-Yang Lee, Yeong-Chin Jou, Chun-Liang Tung, Wei-Hong Lai, Chi-Feng Hung, Meilin Wang, Ya-Yan Lai, Pi-Che Chen, Shu-Fen Wu
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2025-04-01
Edice:	Cells
Témata:	upper tract urothelial carcinoma tumor tissue culture supernatant neutrophils arginase-1 T cells
On-line přístup:	https://www.mdpi.com/2073-4409/14/9/660
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