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Methylation of the Corticotropin Releasing Hormone Gene Promoter in BeWo Cells: Relationship to Gene Activity

Corticotropin releasing hormone (CRH) production by the human placenta increases exponentially as pregnancy advances, and the rate of increase predicts gestational length. CRH gene expression is regulated by cAMP in trophoblasts through a cyclic AMP-response element (CRE), which changes its transcri...

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Principais autores: Xin Pan, Maria Bowman, Rodney J. Scott, John Fitter, Richard C. Nicholson, Roger Smith, Tamas Zakar
Formato: Artigo
Idioma:Inglês
Publicado: Wiley 2015-01-01
Series:International Journal of Endocrinology
Acceso en liña:http://dx.doi.org/10.1155/2015/861302
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