Pharmacological inhibition of SUMOylation with TAK-981 mimics genetic HypoSUMOylation in murine perigonadal white adipose tissue

Post-translational modification by the small ubiquitin-like modifier (SUMO) is essential for cellular differentiation and homeostasis. Here, we investigate the role of SUMOylation in adipose tissue development using TAK-981, a pharmacological inhibitor of SUMOylation. Administration of TAK-981 to mi...

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Главные авторы:	Damien Dufour, Xu Zhao, Florian Chaleil, Patrizia Maria Christiane Nothnagel, Magnar Bjørås, Anne-Marie Lefrançois-Martinez, Antoine Martinez, Pierre Chymkowitch
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Taylor & Francis Group 2025-12-01
Серии:	Adipocyte
Предметы:	SUMOylation adipose tissue adipogenesis inflammation TAK-981
Online-ссылка:	https://www.tandfonline.com/doi/10.1080/21623945.2025.2474107
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