Synthesis and biological evaluation of ibuprofen/o-vanillin Schiff base complexes with anti-inflammatory, anti-proliferative and anti-SARS-COV-19 activities

Abstract This study presents the synthesis and comprehensive characterization of four novel metal-complexes formed from the reaction of copper(II), nickel(II), zinc(II), and vanadium(IV) salts with the bidentate ibuprofen Schiff base ligand (HL) in 1:1 metal-to-ligand ratio. The copper complex shows...

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主要な著者:	Laila H. Abdel-Rahman, Doaa Abou El-ezz, Abdel-Mawgoud M. Abdel-Mawgoud, Mohamed R. Shehata, Mahmoud Abd El Aleem Ali Ali El-Remaily, Mohamed Abdel-Hameed, Shaaban K. Mohamed
フォーマット:	Artigo
言語:	Inglês
出版事項:	Nature Portfolio 2026-03-01
シリーズ:	Scientific Reports
主題:	Ibuprofen o-vanillin Antimicrobial Anticancer DNA interaction DFT
オンライン･アクセス:	https://doi.org/10.1038/s41598-026-38270-8
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