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Cytochrome P450 dependent free radical processes in the liver microsomes of rats administered diethyl phthalate

Diethyl phthalate (DEP) is widely used as a plasticizer and aromatic additive in various consumer products. Biotransformation of this xenobiotic occurs through the cytochrome P450 (CYP) -hydroxylating system, the catalytic cycle of which is accompanied by ROS generation in uncoupling reactions. The...

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Autors principals: О. V. Kеtsa, М. М. Маrchenko
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences of Ukraine, Palladin Institute of Biochemistry 2025-08-01
Col·lecció:The Ukrainian Biochemical Journal
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Accés en línia:http://ukrbiochemjournal.org/wp-content/uploads/2025/09/Ketsa_97_4.pdf
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