Mitochondrial lipid peroxidation is necessary but not sufficient for induction of ferroptosis

Ferroptosis, a form of regulated cell death mediated by lipid peroxidation (LPO), has become the subject of intense research due to its potential therapeutic applications in cancer chemotherapy as well as its pathophysiological role in ischemic organ injury. The role of mitochondrial lipid peroxidat...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	He Huan, Konstantin G. Lyamzaev, Alisa A. Panteleeva, Boris V. Chernyak
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2024-09-01
Schriftenreihe:	Frontiers in Cell and Developmental Biology
Schlagworte:	ferroptosis ferric ammonium citrate (FAC) buthionine sulfoximine (BSO) mitochondrial lipid peroxidation mitochondrial-targeted antioxidants
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fcell.2024.1452824/full
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