Tracking leukemic T‐cell transcriptional dynamics in vivo with a blood‐based reporter assay

Transcriptional dynamics of cancer cells govern cell fate decisions and are therapeutically actionable drug targets. In this study, we engineered a circulating cancer cell line that secretes a luciferase reporter to capture constitutive and circadian clock‐driven transcription dynamics over the cour...

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Autores principales:	Alfred G. Tamayo, Syukri Shukor, Alexandra Burr, Patrick Erickson, Biju Parekkadan
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Wiley 2020-09-01
Colección:	FEBS Open Bio
Materias:	circadian clocks leukemic T cells secreted luciferase transcriptional reporter
Acceso en línea:	https://doi.org/10.1002/2211-5463.12940
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