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The CYP2J2 G-50T polymorphism and myocardial infarction in patients with cardiovascular risk profile

<p>Abstract</p> <p>Background</p> <p>Cytochrome P450 (CYP) enzyme 2J2, an epoxygenase predominantly expressed in the heart, metabolises arachidonic acid to biologically active eicosanoids. One of the CYP2J2 products, 11, 12-epoxyeicosatrienoic acid, has several vasoprotective effects. The CYP2J2-G-5...

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Autori principali: Epplen Jörg T, Mügge Andreas, Neubauer Horst, Hanefeld Christoph, Bulut Daniel, Börgel Jan, Holland-Letz Tim, Spiecker Martin
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2008-12-01
Serie:BMC Cardiovascular Disorders
Accesso online:http://www.biomedcentral.com/1471-2261/8/41
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