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Exploring the prognostic implications of cuproptosis-associated alterations in clear cell renal cell carcinoma via in vitro experiments

Abstract This study investigated the impact of novel copper ionophores on the prognosis of clear cell renal cell carcinoma (ccRCC) and the tumor microenvironment (TME). The differential expression of 10 cuproptosis and 40 TME-pathway-related genes were measured in 531 tumor samples and 71 adjacent k...

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Principais autores: Zhaoyu Xing, Li Cui, Yuehua Feng, Yang Yang, Xiaozhou He
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Portfolio 2024-07-01
coleção:Scientific Reports
Assuntos:
Cuproptosis
TME
ccRCC
Immune response
Immunosuppressive
Acesso em linha:https://doi.org/10.1038/s41598-024-67756-6
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