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Early gut microbiota signature of aGvHD in children given allogeneic hematopoietic cell transplantation for hematological disorders

Abstract Background The onset of acute Graft-versus-Host Disease (aGvHD) has been correlated with the gut microbiota (GM) composition, but experimental observations are still few, mainly involving cohorts of adult patients. In the current scenario where fecal microbiota transplantation has been used...

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Principais autores: Elena Biagi, Daniele Zama, Simone Rampelli, Silvia Turroni, Patrizia Brigidi, Clarissa Consolandi, Marco Severgnini, Eleonora Picotti, Pietro Gasperini, Pietro Merli, Nunzia Decembrino, Marco Zecca, Simone Cesaro, Maura Faraci, Arcangelo Prete, Franco Locatelli, Andrea Pession, Marco Candela, Riccardo Masetti
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2019-03-01
Serier:BMC Medical Genomics
Fag:
Gut microbiota
Hematopoietic stem cell transplantation
Acute graft-versus-host disease
Alloreactivity
16S rRNA gene sequencing
Pediatric patients
Online adgang:http://link.springer.com/article/10.1186/s12920-019-0494-7
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