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Spatiotemporal orchestration of macrophage activation trajectories by Vγ4 T cells during skin wound healing

Summary: Dysregulated macrophage polarization from pro-inflammatory M1 to anti-inflammatory M2 phenotypes underlies impaired cutaneous wound healing. This study reveals Vγ4+ γδ T cells spatiotemporally calibrate macrophage trajectories during skin repair via sophisticated interferon-γ (IFN-γ) condit...

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Principais autores: Wengang Hu, Xiaorong Zhang, Zhongyang Liu, Jiacai Yang, Hao Sheng, Zhihui Liu, Cheng Chen, Ruoyu Shang, Yunxia Chen, Yifei Lu, Xiaohong Hu, Yong Huang, Wenjing Yin, Xin Cai, Dejiang Fan, Lingfeng Yan, Jianlei Hao, Gaoxing Luo, Weifeng He
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2024-04-01
coleção:iScience
Assuntos:
Biological sciences
Immune response
Components of the immune system
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2589004224007673
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