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Cortisol Co-Secretion and Clinical Usefulness of ACTH Stimulation Test in Primary Aldosteronism: A Systematic Review and Biases in Epidemiological Studies

The hypothalamus-pituitary-adrenal (HPA) axis plays an important role in primary aldosteronism. Aldosterone biosynthesis is regulated not only by angiotensin II in the renin-angiotensin-aldosterone system, but also by adrenocorticotropic hormone (ACTH), one of the key components of the HPA axis. Alt...

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Principais autores: Kosuke Inoue, Takumi Kitamoto, Yuya Tsurutani, Jun Saito, Masao Omura, Tetsuo Nishikawa
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021-03-01
Serier:Frontiers in Endocrinology
Fag:
cortisol
ACTH
primary aldosteronism
systematic review
bias
epidemiological methods
Online adgang:https://www.frontiersin.org/articles/10.3389/fendo.2021.645488/full
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