Peritoneal resident macrophages constitute an immunosuppressive environment in peritoneal metastasized colorectal cancer

Abstract Patients with peritoneal metastasized colorectal cancer (PM-CRC) have a dismal prognosis. We hypothesized that an immunosuppressive environment in the peritoneal cavity underlies poor prognosis. We define the composition of the human peritoneal immune system (PerIS) using single-cell techno...

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Bibliografiske detaljer

Principais autores:	J. Saris, A. Y. F. Li Yim, S. Bootsma, K. J. Lenos, R. Franco Fernandez, H. N. Khan, J. Verhoeff, D. Poel, N. M. Mrzlikar, L. Xiong, M. P. Schijven, N. C. T. van Grieken, O. Kranenburg, M. E. Wildenberg, A. Logiantara, C. Jongerius, J. J. Garcia Vallejo, S. S. Gisbertz, S. Derks, J. B. Tuynman, G. R. A. M. D’Haens, L. Vermeulen, J. Grootjans
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Portfolio 2025-04-01
Serier:	Nature Communications
Online adgang:	https://doi.org/10.1038/s41467-025-58999-6
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