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Pax6 mutant cerebral organoids partially recapitulate phenotypes of Pax6 mutant mouse strains.

Cerebral organoids show great promise as tools to unravel the complex mechanisms by which the mammalian brain develops during embryogenesis. We generated mouse cerebral organoids harbouring constitutive or conditional mutations in Pax6, which encodes a transcription factor with multiple important ro...

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Detaylı Bibliyografya
Asıl Yazarlar: Nurfarhana Ferdaos, Sally Lowell, John O Mason
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science (PLoS) 2022-01-01
Seri Bilgileri:PLoS ONE
Online Erişim:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0278147&type=printable
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