Vitamin D deficiency exacerbates bleomycin-induced pulmonary fibrosis partially through aggravating TGF-β/Smad2/3-mediated epithelial-mesenchymal transition

Abstract Background Our earlier report indicated that active vitamin D3 inhibited epithelial-mesenchymal transition (EMT) in bleomycin (BLM)-induced pulmonary fibrosis. The objective of this study was to further investigate whether vitamin D deficiency exacerbates BLM-induced pulmonary fibrosis. Met...

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主要な著者:	Se-Ruo Li, Zhu-Xia Tan, Yuan-Hua Chen, Biao Hu, Cheng Zhang, Hua Wang, Hui Zhao, De-Xiang Xu
フォーマット:	Artigo
言語:	Inglês
出版事項:	BMC 2019-11-01
シリーズ:	Respiratory Research
主題:	Pulmonary fibrosis Vitamin D deficiency Epithelial-mesenchymal transition Bleomycin Mice
オンライン･アクセス:	http://link.springer.com/article/10.1186/s12931-019-1232-6
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