Application of Pharmacokinetic and Pharmacodynamic Analysis to the Development of Liposomal Formulations for Oncology

Liposomal formulations of anticancer agents have been developed to prolong drug circulating lifetime, enhance anti-tumor efficacy by increasing tumor drug deposition, and reduce drug toxicity by avoiding critical normal tissues. Despite the clinical approval of numerous liposome-based chemotherapeut...

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Bibliografische gegevens

Hoofdauteurs:	Sihem Ait-Oudhia, Donald E. Mager, Robert M. Straubinger
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	MDPI AG 2014-03-01
Reeks:	Pharmaceutics
Onderwerpen:	liposomes nanoparticulate drug carriers drug delivery pharmacokinetics pharmacodynamics mathematical simulation
Online toegang:	http://www.mdpi.com/1999-4923/6/1/137
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