Diversification in the HIV-1 Envelope Hyper-variable Domains V2, V4, and V5 and Higher Probability of Transmitted/Founder Envelope Glycosylation Favor the Development of Heterologous Neutralization Breadth.

A recent study of plasma neutralization breadth in HIV-1 infected individuals at nine International AIDS Vaccine Initiative (IAVI) sites reported that viral load, HLA-A*03 genotype, and subtype C infection were strongly associated with the development of neutralization breadth. Here, we refine the f...

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Principais autores:	S Abigail Smith, Samantha L Burton, William Kilembe, Shabir Lakhi, Etienne Karita, Matt Price, Susan Allen, Eric Hunter, Cynthia A Derdeyn
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Public Library of Science (PLoS) 2016-11-01
סדרה:	PLoS Pathogens
גישה מקוונת:	https://doi.org/10.1371/journal.ppat.1005989
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