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Impact of TP53 Codon 72 and MDM2 Promoter 309 Allelic Dosage in a Moroccan Population with Hepatocellular Carcinoma

Single-nucleotide polymorphisms (SNPs) in codon 72 of the TP53 gene (rs1042522) and in the promoter region of the MDM2 gene (SNP309; rs2279744) have been shown to play a role in the predisposition to many cancers. However, these findings were inconsistent in other tumor types, and ethnicity is suspe...

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Bibliografiske detaljer
Principais autores: Sayeh Ezzikouri, Abdellah Essaid El Feydi, Rajae Afifi, Mustapha Benazzouz, Mohammed Hassar, Pascal Pineau, Soumaya Benjelloun
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publishing 2011-07-01
Serier:The International Journal of Biological Markers
Online adgang:https://doi.org/10.5301/JBM.2011.8881
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